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Since the publication of the original edition in 1982,
pesticide-related poisonings, both single cases and epidemic-scale
situations, have continued to occur unabated. This new edition of
Pesticides and Neurological Diseases reviews current literature
describing the effects of insecticides (chlorinated hydrocarbons,
organophosphorus and carbamate esters, and the pyrethroid esters),
fungicides (organomercurials, dithiocarbamates), and herbicides
(chlorophenoxy acids and esters) on the mammalian nervous system.
Acute and chronic exposures have resulted in both subtle and
serious neurological deficits in the peripheral and central nervous
systems, marked by transient effects preceding those of delayed
onset and of persistent duration. The chapters have been largely
revised and rewritten to introduce newer theories of mechanism(s)
of action studied at the laboratory bench. New findings and
observations on human intoxications are included as well.
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